Where research excellence meets patient-centered care.

Dr. Mesiwala has had a leading role in the development of new procedures for treating complex conditions, deformities and injuries of the spine. Since 2004, he has performed more than 8,000 operations in his private practice, including more than 750 minimally invasive sacroiliac (SI) fusions, 1,000 disc replacements and 850 spinal cord stimulator procedures. He performs more than 200 disc replacement surgeries every year, and has one of the largest and most comprehensive sacroiliac practices in the world. His interests also include peripheral nerve surgery.

  • OCMA 2023 Physicians of Excellence

Internationally trained, Dr. Mesiwala brings a “solutions-oriented” approach to providing compassionate patient care. He helps patients understand the often-complex problems that may be key to restoring function and improving quality of life.

Dr. Mesiwala’s career began at Johns Hopkins University, in Baltimore, where he graduated summa cum laude with a bachelor’s degree in biomedical engineering, then continued to medical school at the University of California, San Francisco. Following that, he completed both a general surgery internship and neurosurgery residency at the University of Washington, in Seattle. The next phase of Dr. Mesiwala’s training took him oversees. At Atkinson Morley’s Hospital, near London, he was senior registrar of neurological surgery, which is equivalent to chief resident. Next, he completed his first fellowship in skull base surgery at International Neurosciences Institute in Hanover, Germany. Afterward, Dr. Mesiwala returned to the University of Washington, where he served as chief resident for neurological surgery. There, he also completed a second fellowship in cerebrovascular/skull base surgery, followed by a third fellowship at the University of Pittsburgh, in Pennsylvania.


Prior to DISC, Dr. Mesiwala was the attending neurosurgeon at Cedars-Sinai Medical Center, in Los Angeles. He has authored more than 50 peer-reviewed articles, book chapter and abstracts, and holds several patents for medical devices used in spinal surgery. Additionally, he has shared his expertise on several radio and television programs. Dr. Mesiwala is a fellow of the American Association of Neurological Surgeons (FAANS) and active in the American Medical Association, Congress of Neurological Surgeons, The Pituitary Network, Trigeminal Neuralgia Association and Indian Medical Association.

Outside the operating room, Dr. Mesiwala is a philanthropist with a passion for helping others. He lives his life to the fullest, enjoying travel, wildlife photography, nature conservation, food, automotive projects, emerging technology and time with his family.

Dr. Mesiwala in the News

TIME: How to Exercise When It's Really Hot Outside

Outpatient Surgery: Eliminate All Variables

Nike Blog: How To Tell If You Have Heat Exhaustion — And What To Do About It, According To Doctors

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  • University of Washington, Seattle —Cerebrovascular/Skull Base
  • International Neurosciences Institute, Hanover, Germany — Cerebrovascular/Skull Base
  • University of Pittsburgh, Pennsylvania — Cerebrovascular/Skull Base  


  • Senior Registrar, Atkinson Morley’s Hospital/National Health Service, London, England — Neurological Surgery
  • University of Washington, Seattle — Neurological Surgery


  • University of Washington, Seattle — General Surgery

Medical School

  • University of California, San Francisco


  • Johns Hopkins University, Baltimore
  • Summa cum laude


Diplomate, American Board of Neurological Surgery

California Medical Licensure



  • American Association of Neurological Surgeons
  • American Medical Association
  • Congress of Neurological Surgeons
  • Society of Lateral Access Surgeons
  • SI Joint Society – Founding Member
  • International Society for Minimal
  • Intervention in Spinal Surgery – Board Member
  • North American Spine Society


Cedars-Sinai Medical Center - Maxine Dunitz Neurosurgical Institute

  • Los Angeles, CA
  • Attending Neurosurgeon
  • July 2004 – June 2005

Southern California Center for Neuroscience and Spine

  • Pomona, Santa Ana, and San Bernardino, CA
  • Director, Neurological Surgery
  • September 2005 - Present

St. Bernardine Medical Center

  • San Bernardino, CA
  • Chief, Department of Surgery
  • Jan 2016 – 2018

Snoop Youth Football League

  • Pomona, CA
  • Medical Director
  • 2015 - 2019


Minimally Invasive Spine Surgery
Microscopic Spinal Surgery
Reconstructive Spinal Surgery
Neurosurgery / Brain Surgery



  • St. Bernardine Hospital Medical Center, San Bernardino, CA
  • San Antonio Regional Hospital, Upland, CA
  • San Dimas Community Hospital, San Dimas, CA
  • Archibald Surgery Center, Rancho Cucamonga, CA
  • Mid Valley Surgery Center, Ontario, CA
  • DISC Newport, Newport Beach, CA